HIV drug resistance
نویسندگان
چکیده
منابع مشابه
HIV drug resistance in HIV-infected children.
Almeida et al. report, in this issue of the journal, a retrospective studyon theprevalence and patterns of antiretroviral drug resistance in 24 treatment-naïve and 23 treatment-experienced children failing therapy between 2000 and 2004 attending a clinic in São Paulo. All children were vertically infected, and the median age of the naïveand treatment-experienced children was 22 months and 102 m...
متن کاملHIV-1 drug resistance and resistance testing.
The global scale-up of antiretroviral (ARV) therapy (ART) has led to dramatic reductions in HIV-1 mortality and incidence. However, HIV drug resistance (HIVDR) poses a potential threat to the long-term success of ART and is emerging as a threat to the elimination of AIDS as a public health problem by 2030. In this review we describe the genetic mechanisms, epidemiology, and management of HIVDR ...
متن کاملReversibility of HIV drug resistance.
Using a mathematical model, Blower et al. (1) predicted the impact of antiretroviral therapy (ART) on future trends in the sexual spread of human immunodeficiency virus (HIV). The model employed Latin hypercube sampling to allow for the high degree of uncertainty in the estimation of many model parameters. The authors incorporated into their model the assumption that patients with drug-resistan...
متن کاملHiv-1 Drug Resistance Mutations
Non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens have recently been used in HIV-1 infected children in resource-limited settings. Treatment failure with this regimen has become more common. A second regimen needs to be prepared for the Thai national program. Genotypic resistance testing was conducted among HIV-1 infected children who experienced virological failure with ant...
متن کاملPredicting HIV drug resistance with neural networks
MOTIVATION Drug resistance is a very important factor influencing the failure of current HIV therapies. The ability to predict the drug resistance of HIV protease mutants may be useful in developing more effective and longer lasting treatment regimens. METHODS The HIV resistance is predicted to two current protease inhibitors, Indinavir and Saquinavir. The problem was approached from two pers...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: HIV Clinical Trials
سال: 2002
ISSN: 1528-4336,1945-5771
DOI: 10.1310/kmkn-ke48-2gwu-g0he